For me as an immunolgist, the analysis of immunogenetics
data is key. In early days and still now many tools
developed in bioinformatics are not specific enough to
analyse immunogenetics data. Therefore, I developed
specific tools and databases in the past and continue now.
I was initially involved in the establishment of the
IMGT database. After six
years, I decided to follow a different direction. The key
program, written in ANSI-C is the DNAPLOT programm. Using
DNAPLOT as the central tool, specific Web based programms were
developed for the analysis of Immunoglobulin genes and HLA
sequences. The central component of the DNAPLOT programm,
the aligner, is patented (DE0019950059C2). It was utilized
as a search engine for the VBASE database. The
latest Development is the VBASE2 database.
DNAPLOT and EU-Gene are registered Trademarks of
EU-Gene.